Cancer-Carcinoma of the Breast:
Mansell P.W.A., Ichinose H., Reed R.J., Krements E.T., McNamee R.B., Di Luzio N.R.; “Macrophage-mediated Destruction of Human Malignant Cells in Vitro”. Journal of National Cancer Institute; 54: 571-580. 1975.
Direct Quote: “The initial 9 patients studied had malignant carcinoma of the breast. Control and experimental lesions were injected; subsequently biopsies were performed at varying intervals for histologic evaluation. Always when glucan or glucan and RF fraction were administered intra-lesionally, the size of the lesion was strikingly reduced in as short a period as 5 days. …In small lesions, resolution was complete, whereas in large lesions, resolutions was partial.”
DiLuzio N.R. Williams D.L. et al, “Comparative evaluation of the tumor inhibitory and antibacterial activity of solubilized and particulate glucan,” Recent Results Cancer Res 75:165-172. 1980.
Direct Quote: “Intravenous administration of soluble or particulate glucan resulted in significant reduction in the growth of a syngeneic anaplastic mammary carcinoma and melanoma B16 and enhanced survival.”
Proctor, et al., “Development of a Bioassay for Anti-Tumor Activity of the Reticuloendoethelial Stimulant Class: Reproducibility of the Bioassay”. J. Immunopharmacol.; 3: 385-395. 1981-1982.
Direct Quote: “Intravenously administered DiLuzio glucan…caused dose dependent increases in the tumor cell loss from the lungs of …mice challenged respectively with intravenous 125IuDR labelled B16 or T 1699 mammary carcinoma cells.”
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