Cancer - Radiotherapy:
Gu YH, Takagi Y, et al; "Enhancement of radioprotection and anti-tumor immunity by yeast-derived beta-glucan in mice," J Med Food. 8(2) 154-8; Dept of Radiological Technology, Suzuka U of Med Sc, Suzuka, Japan, Summer 2005.
Direct Quote: "Intraperitoneal injection of beta-glucan was shown to greatly delay mortality in mice exposed to whole-body X-ray radiation and tumor growth in tumor-bearing mice. ...Augmented immunological activity as seen in increased NK (natural killer) and LAK (lymphokine-activated killer) activity by beta-glucan seems to play a role in preventing secondary infections associated with irradiation and probably contributes to the attenuated [reduced] tumor growth in tumor-bearing mice through enhanced anti-tumour immunity. These results suggest that beta-glucan may be a promising adjunct treatment for cancer patients receiving radiotherapy."
Carrow, D.J.; “Beta-1,3-glucan as a Primary Immune Activator,” Townsend Letter; June 1996.
Direct Quote: “Over the past 11 months I have been able to convince five out of eight breast cancer patients who were undergoing radiation therapy, to consume one capsule of beta 1,3/1,6 glucan (NSC-24 3 mg) three times per day. To date, I have observed that none of the patients using NSC-24 have suffered from any type of radiation injury to the skin, while the three patients who chose not to use NSC-24 all show signs of extensive radiation damage to the skin.”
Kobayashi H, Yoshida R, Kanada Y, Fukuda Y, Yagyu T, Inagaki K, Kondo T, Kurita N, Suzuki M, Kanayama N, Terao T., “Suppressing effects of daily oral supplementation of beta-glucan extracted from Agaricus blazei Murill on spontaneous and peritoneal disseminated metastasis in mouse model. ”Dept of Obstetrics and Gynecology, Hamamatsu U Sch of Med; J Cancer Res Clin Oncol. 5 May 10, 2005.
Direct Quote: “Conclusion: Treatment with beta-glucan may be beneficial for cancer patients with or at risk for metastasis.”
Williams D.L., Browder I. and DiLuzio N.R., “Methods and compositions for prophylactic and therapeutic treatment of infections,” U.S. Patent 4900722, Issued Feb 13, 1990.
Direct Quote: “The soluble phosphorylated glucans are also useful for stimulating macrophage cells, either in vivo or in vitro, to produce a cytotoxic/cyctostatic factor effective against cancer cells.” [cytotoxic: toxic to cell - prevents reproduction or growth]
Sveinbj B, Seternes O, Seljelid R, “Macrophage cytotoxicity against murine meth A sarcoma involves nitric oxide-mediated apoptosis,” Biochem Biophys Res Commun, 223:3, 643-9. Jun 1996.
Direct Quote: “When stimulated with interferon-gamma and soluble beta 1,3-D-glucan, macrophages exerted cytotoxicity towards syngeneic Meth A [sarcoma] tumor cells.”
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