Wound Healing:
Leibovich S.J., et al., “Promotion of Wound Repair in Mice by Application of Glucan”. J. Reticuloendothel, Soc. 27: 1-11. 1980
Direct Quote: “Of all the substances tested, glucan was the only substance to exhibit a particularly marked enhancement of the proliferative phase of wound healing. It appears, from these experiments, that the effect observed by others in terms of the activation of reticuloendothelial [immune response] function by glucan and the activation of macrophages, both locally and systematically, also apply to activation of macrophages in healing wounds.”
Portera CA, Love EJ, Memore L, Zhang L, Muller A, Browder W, Williams DL; “Effect of macrophage stimulation on collagen biosynthesis in the healing wound,” Am Surg, 63:2,125-131. Feb 1997.
Direct Quote: “…macrophage modulation with glucan phosphate will increase tensile strength in experimental colon and skin wounds. In addition, we have observed a positive correlation between glucan phosphate treatment, wound tensile strength, and collagen biosynthesis.”
Williams D.L., Browder I. and DiLuzio N.R., “Soluble phosphorylated glucan: methods and compositions for wound healing,” U.S. Patent 4975421, Issued Dec 4, 1990.
Direct Quote: “The soluble phosphorylated glucans are useful for promoting the wound healing process. The soluble phosphorylated glucans are also useful for prophylactic and therapeutic applications against neoplastic, bacteria, viral, fungal and parasitic diseases.”
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